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The application and mechanism of action of ribavirin in therapy of hepatitis C
Journal article   Open access

The application and mechanism of action of ribavirin in therapy of hepatitis C

Emmanuel Thomas, Marc G Ghany and T Jake Liang
Antiviral chemistry & chemotherapy, Vol.23(1), pp.1-12
2012-09-25
PMCID: PMC6271563
PMID: 22592135

Abstract

Antiviral Agents - pharmacology Animals Hepatitis C - drug therapy Antiviral Agents - therapeutic use Humans Ribavirin - therapeutic use Ribavirin - pharmacology
Ribavirin has been used as an antiviral agent for several decades. Although it has activity against numerous viruses, its major use clinically has been in the treatment of respiratory syncytial virus in paediatric patients and chronic HCV infection in both children and adults. This review highlights the clinical application and mechanism of action of ribavirin and discusses the future role of ribavirin in treatment of HCV where there are intense research efforts to improve therapy.
url
https://doi.org/10.3851/IMP2125View
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