Abstract
To compare endophthalmitis rates after 20-gauge versus 23-gauge versus 25-gauge pars plana vitrectomy (PPV) in 2007–2008, and compare the rates with those of 2005–2006.Multicenter study including all patients who developed endophthalmitis following PPV performed by any of the authors during 2005–2008, and all patients who developed endophthalmitis following PPV at Penn State College of Medicine and Bascom Palmer Eye Institute during 2005–2008. The endophthalmitis rates after 20-gauge, 23-gauge and 25-gauge PPV during 2007–2008 were compared to those from 2005–2006.The endophthalmitis incidence during 2007–2008 was 1/4,403 (0.02%) for 20-gauge PPV, 1/3,362 (0.03%) for 23-gauge PPV, and 1/789 (0.13%) for 25-gauge PPV. There is no significant difference among these rates between any two of the three groups. Compared with the endophthalmitis rates among the same group of surgeons during 2005–2006, the 2007–2008 endophthalmitis rates following 20-gauge and 23-gauge PPV were stable, and the rate following 25-gauge PPV was marginally lower (p = 0.056; odds ratio = 0.15; 95% CI: (0.003, 1.03)).There was no significant difference in the 2007–2008 rates of endophthalmitis following 20-gauge versus 23-gauge versus 25-gauge PPV; among the same group of surgeons, the 2007–2008 rate of endophthalmitis following 25-gauge PPV was marginally lower than the 2005–2006 rate.
