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The role of p53 in limiting somatic cell reprogramming
Journal article   Open access  Peer reviewed

The role of p53 in limiting somatic cell reprogramming

Yan Liu, Ruben Hoya-Arias and Stephen D Nimer
Cell research, Vol.19(11), pp.1227-1228
2009-11
PMID: 19881523

Abstract

Induced Pluripotent Stem Cells - pathology Cell Cycle - genetics Genomic Instability Proto-Oncogene Proteins c-mdm2 - genetics Tumor Suppressor Protein p53 - antagonists & inhibitors Fibroblasts - physiology Humans Gene Expression Regulation Tumor Suppressor Protein p53 - metabolism Cyclin-Dependent Kinase Inhibitor p16 - genetics Apoptosis - genetics Cyclin-Dependent Kinase Inhibitor p16 - antagonists & inhibitors Tumor Suppressor Protein p53 - genetics Cellular Reprogramming Animals Cyclin-Dependent Kinase Inhibitor p21 - genetics Cell Transformation, Neoplastic Cyclin-Dependent Kinase Inhibitor p16 - metabolism Cyclin-Dependent Kinase Inhibitor p21 - metabolism Hematopoietic Stem Cells - physiology Mice Mutagenesis, Insertional Proto-Oncogene Proteins c-mdm2 - metabolism Induced Pluripotent Stem Cells - metabolism
url
https://doi.org/10.1038/cr.2009.121View
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Citation topics
1 Clinical & Life Sciences
1.102 Stem Cell Research
1.102.622 Pluripotency
Web Of Science research areas
Cell Biology
ESI research areas
Molecular Biology & Genetics

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#3 Good Health and Well-Being

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