Abstract
Bone-forming tumors of the skeletal system represent a broad spectrum of neoplasms that vary significantly in their morphology and biologic potential. They arise within or on the surface of bone and are recognized histologically by the juxtaposition of the neoplastic cells and tumor bone matrix which may or may not be mineralized. The morphological features of the tumor cells and matrix vary with the biological potential of the tumor. Bone-forming tumors are uncommon and this fact, in combination with their morphologic heterogeneity, makes their diagnosis notoriously difficult. Because treatment may vary from observation to en bloc excision with neoadjuvant therapy, careful correlation of tumor morphology with clinicoradiographic features is paramount for accurate diagnosis and appropriate clinical management.