Abstract
Liver transplantation is a life-saving intervention for patients with ALF and end-stage liver disease, as well as selected candidates with specific metabolic and inherited liver diseases, vascular disorders, and primary hepatic malignancies. Excellent graft and patient survival rates reflect improved selection of transplant candidates, advances in surgical technique, postoperative care, and immunosuppression. The pretransplant evaluation is a multidisciplinary process intended to recognize and treat important comorbid conditions that may impair outcomes during the peri- and post-transplant periods. Prevention, early identification, and timely treatment of infectious, biliary, and vascular complications decrease morbidity and improve graft and patient survival. Comprehensive long-term care of liver transplant recipients remains critical to improved outcomes.