Abstract
As a result of the large and increasing flow of international migrants, scholarly interest in acculturation, and its links with positive and negative indicators of psychosocial functioning, has substantially increased over the last few decades. This entry reviews contemporary models of acculturation, the role of acculturation in substance use among adolescents from immigrant families, and methodological and conceptual limitations that have characterized the field of acculturation and health disparities. In doing so, the present entry is intended to stimulate innovative and informative work that further illuminates the relationship between acculturation and substance use.