Abstract
Numerous skin conditions have been associated with stress through both a cause and effect relationship. Both acne and rosacea are such diseases. Although various efforts have been made in order to understand the pathogenesis behind this unique association between these conditions and psychological stressors, there is still much more that needs to be done in order to fully understand this relationship. Underlying inflammation, oxidative stress, and other pathogenic processes have all been contributed to this relationship. However, the true nature of this connection between stress and the skin remains a mystery. In this chapter, we discuss this relationship and the current understanding of unique phenomenon.