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Application of Plasma Level Determinations to Antiarrhythmic Drug Management: Integration with Various End-points of Therapy
Book chapter

Application of Plasma Level Determinations to Antiarrhythmic Drug Management: Integration with Various End-points of Therapy

Robert J Myerburg, Kenneth M Kessler, Liaqat Zaman, Richard G Trohman, Nadir Saoudi and Agustin Castellanos
Therapeutics in Cardiology, pp.79-91
Developments in Cardiovascular Medicine, Springer Netherlands
DOI: https://doi.org/10.1007/978-94-009-1333-2_11

Abstract

Antiarrhythmic Drug Cardiac Arrest Antiarrhythmic Agent Ventricular Tachycardia Premature Ventricular Contraction
Therapeutic effectiveness of antiarrhythmic agents, defined as the prevention of lethal or potentially lethal arrhythmias, must incorporate considerations of 3 elements: the forms and/or frequency of chronic ventricular arrhythmias, as well as the characteristics of arrhythmias labeled as ‘potentially lethal’;the clinical settings in which various forms of ventricular arrhythmias occur; andthe validity of end-points used to guide antiarrhythmic therapy.

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