Chemical Delivery Systems

doi:10.1002/9781118407738.ch6

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Book chapter

Chemical Delivery Systems

Retrometabolic Drug Design and Targeting, pp.259-393

John Wiley & Sons, Inc

2012-10-05

DOI: https://doi.org/10.1002/9781118407738.ch6

Abstract

CDSs and sequential metabolic conversion

BBB disruption for drug delivery to brain

bioremovable, T moieties and modifier functions

CDS novel methodologies targeting specific sites

enzymatic, brain‐targeting/and eye‐targeting CDSs

This chapter contains sections titled: Enzymatic Physicochemical‐Based (Brain‐Targeting) CDSs Site‐Specific Enzyme‐Activated (Eye‐Targeting) CDSs Receptor‐Based Transient Anchor‐Type CDSs References

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Title: Chemical Delivery Systems
Contributors: Nicholas Bodor (Editor) - Center for Drug Discovery, University of Florida, Gainesville, Florida, USA
Peter Buchwald (Editor) - Diabetes Research Institute and Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, Florida, USA
Publication Details: Retrometabolic Drug Design and Targeting, pp.259-393
Publisher: John Wiley & Sons, Inc; Hoboken, NJ, USA
Number of pages: 135
Language: English
Resource Type: Book chapter
Record Identifier: 991031598912502976