Abstract
Endogenous endophthalmitis is the result of hematogenous spread of organisms to the eye from a site of infection elsewhere in the body or from contaminated catheters or needles. The prognosis in endophthalmitis is dependent on culture results, time of onset of the endophthalmitis, and the virulence of the pathogen. Biopsy of intraocular fluid/tissue is the only method that permits reliable diagnosis and treatment. Successful management of infectious endophthalmitis depends on timely diagnosis and institution of appropriate therapy. The different presenting clinical settings, a rational approach to diagnosis, and the treatment of infectious endophthalmitis are reviewed.