Abstract
The evolution of Artificial Intelligence in health and medicine has been paralleled by an extraordinary effort to identify and address the ethical issues raised by this technology. It has become clear that the success of AI in patient care and research is dependent on the success of this effort to address appropriate software quality and standards, explainability and interpretability, transparency and accountability, human control, and bias and fairness. The tools of applied ethics are identified as essential if the growing use of AI is to be trusted and trustworthy and therefore to achieve the benefits for which its promoters, developers, and users hope.