Abstract
The fresh frozen tissue technique was initially used for eyelid tumors; and since its introduction, has revolutionized the way Mohs surgery is performed. It has rapidly expanded beyond eyelid tumors and is now used for all anatomic locations. Now, reconstruction can occur immediately following complete histologic removal of the tumor; which in most instances is the same day. Additionally, the fresh frozen tissue technique is less painful, quicker, and conserves more tissue compared to the fi xed tissue technique. This chapter details the introduction as well as how to perform the fresh frozen tissue technique.