Abstract
Evaluation of the many potential complications in intestinal and multivisceral transplantation is often based on the pathological changes expressed in biopsied tissue from the allograft or native organs. The field of transplant pathology has evolved and now incorporates routine staining of tissue with highly specialized ancillary immunohistochemical and molecular techniques. Moreover, new biomarkers complement these sophisticated histocompatibility evaluations affording the transplant pathologist additional tools to specifically identify one or more complications occurring in grafted gastrointestinal tissue.