Abstract
Mohs micrographic surgeryMohs micrographic surgery (MMS) can be used to treat a wide variety of tumors. General indications for Mohs micrographic surgeryMohs micrographic surgery require continuous growth of cutaneousCutaneous tumors. Additionally, MMS is considered particularly well-suited for tumors that exhibit perineural invasionPerineural invasion, tumors in high-risk anatomical areas, tumors that have been incompletely excised, and those with poorly defined clinical marginsClinical margins. The indications for MMS for each tumor type can be divided into common and uncommon entities. The most common indications for MMS include basal cell carcinomaBasal cell carcinoma (BCC) and cutaneousCutaneoussquamous cell carcinomaSquamous cell carcinoma (CSCC). Less common indications for MMS are not supported by as much evidence but include: cutaneousCutaneousmelanomaMelanoma, Merkel cell carcinomaMerkel cell carcinoma (MCC), dermatofibrosarcoma protuberansDermatofibrosarcoma protuberans (DFSP), microcystic adnexal carcinomaMicrocystic adnexal carcinoma (MAC), atypical fibroxanthomaAtypical fibroxanthoma (AFX), superficial leiomyosarcomaLeiomyosarcoma, sebaceous carcinomaSebaceous carcinoma (SC), and extramammary Paget DiseaseExtramammary Paget’s Disease (EMPD) (EMPD). The evidence behind using MMS will briefly be discussed for each entity, including recommendations from current guidelines such as the Appropriate Use Criteria (AUC), the National Comprehensive Cancer Network (NCCN), and the American Academy of Dermatology (AAD). The recurrence ratesRecurrence rates when using MMS for these tumors will also be addressed.