Mechanism of Drug Action: Basic Concepts

doi:10.1002/9781118407738.ch2

Back

Book chapter

Mechanism of Drug Action: Basic Concepts

Retrometabolic Drug Design and Targeting, pp.9-38

John Wiley & Sons, Inc

2012-10-05

DOI: https://doi.org/10.1002/9781118407738.ch2

Abstract

drug‐likeness and bioavailability challenge

drug action mechanism, BDDCS as alternative to BCS

pharmacodynamic phase, drug–receptor interactions

receptors, enzymes, and molecular mechanics

stimulus–response and ADME behavior

This chapter contains sections titled: Pharmacodynamic Phase: Drug–Receptor Interactions Pharmacokinetic Phase: ADME Structural Requirements: Keeping It “Drug‐Like” References

Metrics

23 Record Views

Details

Title: Mechanism of Drug Action: Basic Concepts
Contributors: Nicholas Bodor (Editor) - Center for Drug Discovery, University of Florida, Gainesville, Florida, USA
Peter Buchwald (Editor) - Diabetes Research Institute and Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, Florida, USA
Publication Details: Retrometabolic Drug Design and Targeting, pp.9-38
Publisher: John Wiley & Sons, Inc; Hoboken, NJ, USA
Number of pages: 30
Language: English
Resource Type: Book chapter
Record Identifier: 991031598912802976