Abstract
Late-onset primary open-angle glaucoma (POAG) is a bilateral disease, which typically has its onset in the fifth or sixth decade of life. The clinical course usually consists of mild to moderately elevated intraocular pressure (IOP), although a significant number of patients may not have a measured IOP greater than the normal range [1]. Optic nerve damage and visual field loss, which may culminate in blindness, occur over many years, usually decades after onset of the disease. The mode of inheritance for late-onset POAG is not known. POAG is considered a complex trait that results from interaction of multiple genes in conjunction with environmental influences.