Abstract
The use of surgical mitral valve replacement with bioprosthetic valves has increased in recent decades. Bioprosthetic valves have many advantages compared to mechanical valves: in particular, they do not require long‐term anticoagulation. Conversely, bioprosthetic valves are prone to degeneration and have limited durability. As the number of surgical mitral valve implantations increases, the number of failed bioprostheses requiring intervention increases as well. Surgical redo of mitral valve replacement carries a high mortality risk, making transseptal transcatheter mitral valve in valve replacement an attractive alternative. Is a safe, elegant, and effective procedure. In this chapter, we will review step by step the percutaneous transseptal approach for mitral valve replacement.