Abstract
Impairments in a variety of cognitive processes, including concentration and
attention, learning and memory, processing speed, and problem solving, are present in
people with schizophrenia. Also seen in the condition are notable impairments in the
ability to perform everyday tasks and to achieve normal functional milestones such as
work, stable social relationships, and living independently. In this article I
discuss recent research that has focused on quantifying the predictors of disability
in real-world functioning, with cognitive impairment being one of the major
predictors. Other important developments include the development of direct measures
of the ability to perform the skills required to achieve everyday functional
goals—skills referred to as “functional capacity.” Studies have shown that these
abilities may be influenced by cognitive impairments and may be better predictors of
disability than are cognitive deficits. I also examine the current literature on the
treatment of cognitive impairments and functional disability, including both
pharmacological and behavioral interventions.