Abstract
The central part of a PMMA or acrylic resin lens was modified into hydrophobic and the peripheral part to be phydrophilic using teh ArF laser and excimer lamp. PMMA or acrylic resin lens have been used as an intraocular lens for 50 years and is the golden standard in ophthalmology. However, protein and fat are stuck onto the IOL surface after long-term implantation and opacify the surface )after-cataract). Therefore, the central part of the IOL was modified to be hydrophobic to prevent fat and protein deposition; the periphery was made hydrophilic to develop affinity for tissue.