Abstract
This dissertation explores the manipulation of molecular behavior within confined spaces using various supramolecular hosts (octa acid, cucurbiturils, cyclodextrins, palladium nanocage). The research demonstrates how confinement influences chemical equilibria by selectively shifting dynamic covalent reactions towards monomeric forms through size-selective recognition and preserving complex equilibria within larger cavities. Furthermore, it showcases successful co-encapsulation strategies for energy storage applications (MOST) and charge transfer complexes, highlighting the crucial role of host cavity dimensions in controlling guest interactions and access. This work advances supramolecular chemistry by establishing design principles for molecular recognition and offering pathways towards selective separations and functional devices.