3-Dimensional Optical Clearing and Imaging of Pruritic Atopic Dermatitis and Psoriasis Skin Reveals Downregulation of Epidermal Innervation

Yingrou Tan; Wei Jie Ng; Sean Zhuo Xuan Lee; Bernett Teck Kwong Lee; Leigh A Nattkemper; Gil Yosipovitch; Lai Guan Ng; Hong Liang Tey

doi:10.1016/j.jid.2018.11.006

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3-Dimensional Optical Clearing and Imaging of Pruritic Atopic Dermatitis and Psoriasis Skin Reveals Downregulation of Epidermal Innervation

Journal article

Open access

Peer reviewed

3-Dimensional Optical Clearing and Imaging of Pruritic Atopic Dermatitis and Psoriasis Skin Reveals Downregulation of Epidermal Innervation

Yingrou Tan, Wei Jie Ng, Sean Zhuo Xuan Lee, Bernett Teck Kwong Lee, Leigh A Nattkemper, Gil Yosipovitch, Lai Guan Ng and Hong Liang Tey

Journal of investigative dermatology, Vol.139(5), pp.1201-1204

2019-05

DOI: https://doi.org/10.1016/j.jid.2018.11.006

PMID: 30471253

Abstract

Immunohistochemistry

Severity of Illness Index

Psoriasis - diagnostic imaging

Epidermis - pathology

Epidermis - diagnostic imaging

Humans

Male

Reference Values

Dermatitis, Atopic - pathology

Voltage-Sensitive Dye Imaging

Case-Control Studies

Pruritus - metabolism

Psoriasis - pathology

Psoriasis - metabolism

Female

Biopsy, Needle

Pruritus - diagnostic imaging

Pruritus - pathology

Imaging, Three-Dimensional

Dermatitis, Atopic - metabolism

Epidermis - innervation

Nerve Endings - pathology

Dermatitis, Atopic - diagnostic imaging

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.65 Allergy; 1.65.1091 Atopic Dermatitis
Web Of Science research areas: Dermatology
ESI research areas: Clinical Medicine

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Details

Title: 3-Dimensional Optical Clearing and Imaging of Pruritic Atopic Dermatitis and Psoriasis Skin Reveals Downregulation of Epidermal Innervation
Creators: Yingrou Tan - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore
Wei Jie Ng - National University of Singapore, Singapore 119077
Sean Zhuo Xuan Lee - Anderson Junior College, Singapore
Bernett Teck Kwong Lee - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore
Leigh A Nattkemper - Department of Dermatology and Cutaneous Surgery and Miami Itch Center, Miller School of Medicine, University of Miami Health System, Miami, Florida, USA
Gil Yosipovitch - Department of Dermatology and Cutaneous Surgery and Miami Itch Center, Miller School of Medicine, University of Miami Health System, Miami, Florida, USA
Lai Guan Ng - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (ASTAR), Biopolis, Singapore. Electronic address: Ng_Lai_Guan@immunol.a-star.edu.sg
Hong Liang Tey - National Skin Centre, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore. Electronic address: teyhongliang111@yahoo.com
Publication Details: Journal of investigative dermatology, Vol.139(5), pp.1201-1204
Publisher: United States
Academic Unit: Miller School of Medicine; UMMG Dept of Dermatology & Cutaneous Surgery
Language: English
Resource Type: Journal article
PMID: 30471253
Record Identifier: 991031577145602976