A Phase 2, randomized, partially blinded, active-controlled study assessing the efficacy and safety of variable anticoagulation reversal using the REG1 system in patients with acute coronary syndromes: results of the RADAR trial

Thomas J Povsic; John P Vavalle; Laura H Aberle; Jaroslaw D Kasprzak; Mauricio G Cohen; Roxana Mehran; Christoph Bode; Christopher E Buller; Gilles Montalescot; Jan H Cornel; Andrzej Rynkiewicz; Michael E Ring; Uwe Zeymer; Madhu Natarajan; Nicolas Delarche; Steven L Zelenkofske; Richard C Becker; John H Alexander

doi:10.1093/eurheartj/ehs232

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A Phase 2, randomized, partially blinded, active-controlled study assessing the efficacy and safety of variable anticoagulation reversal using the REG1 system in patients with acute coronary syndromes: results of the RADAR trial

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A Phase 2, randomized, partially blinded, active-controlled study assessing the efficacy and safety of variable anticoagulation reversal using the REG1 system in patients with acute coronary syndromes: results of the RADAR trial

Thomas J Povsic, John P Vavalle, Laura H Aberle, Jaroslaw D Kasprzak, Mauricio G Cohen, Roxana Mehran, Christoph Bode, Christopher E Buller, Gilles Montalescot, Jan H Cornel, …

European heart journal, Vol.34(31), pp.2481-2489

2013-08-14

DOI: https://doi.org/10.1093/eurheartj/ehs232

PMCID: PMC3895957

PMID: 22859796

Abstract

REG1

Clinical Research

Acute coronary syndromes

Anticoagulation reversal

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 2 Chemistry; 2.145 Biosensors; 2.145.243 Aptamer
Web Of Science research areas: Cardiac & Cardiovascular Systems
ESI research areas: Clinical Medicine

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Title: A Phase 2, randomized, partially blinded, active-controlled study assessing the efficacy and safety of variable anticoagulation reversal using the REG1 system in patients with acute coronary syndromes: results of the RADAR trial
Creators: Thomas J Povsic - Duke Clinical Research Institute, Duke University Medical Center
John P Vavalle - Duke Clinical Research Institute, Duke University Medical Center
Laura H Aberle - Duke Clinical Research Institute, Duke University Medical Center
Jaroslaw D Kasprzak - Medical University of Lodz
Mauricio G Cohen - University of Miami Miller School of Medicine
Roxana Mehran - Mount Sinai School of Medicine
Christoph Bode - University of Freiberg
Christopher E Buller - Hamilton General Hospital
Gilles Montalescot - Institut de Cardiologie, Pitié-Salpétrière Hospital
Jan H Cornel - Medisch Centrum Alkmaar
Andrzej Rynkiewicz - University Clinical Center, Hospital of the Medical University of Gdansk
Michael E Ring - Sacred Heart Medical Center
Uwe Zeymer - Heart Center Ludwigshafen
Madhu Natarajan - Hamilton Health Sciences
Nicolas Delarche - Hospital Francois Mitterand
Steven L Zelenkofske - Regado Biosciences
Richard C Becker - Duke Clinical Research Institute, Duke University Medical Center
John H Alexander - Duke Clinical Research Institute, Duke University Medical Center
Publication Details: European heart journal, Vol.34(31), pp.2481-2489
Publisher: Oxford University Press
Academic Unit: Miller School of Medicine; UMMG Dept of Medicine - Cardiovascular
Language: English
Resource Type: Journal article
PMID: 22859796
PMCID: PMC3895957
Record Identifier: 991031559784602976