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A Random Sequential Adsorption Model for Protein Adsorption to Surfaces Functionalized with Poly(ethylene oxide)
Journal article   Peer reviewed

A Random Sequential Adsorption Model for Protein Adsorption to Surfaces Functionalized with Poly(ethylene oxide)

Parag Katira, Ashutosh Agarwal and Henry Hess
Advanced materials (Weinheim), Vol.21(16), pp.1599-1604
2009-04-27
DOI: https://doi.org/10.1002/adma.200802057

Abstract

self‐assembled monolayers polymeric materials proteins surface functionalization biomedical materials
A random sequential adsorption model for the adsorption of proteins to surfaces functionalized with poly(ethylene oxide)/poly(ethylene glycol) at a range of molecular weights and grafting densities is presented. An excellent fit of the model predictions to experimental results suggests that the random arrangement of polymer chains leading to polymer‐free “bald” spots is a critical factor in primary protein adsorption.

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Citation topics
2 Chemistry
2.53 Polymers & Macromolecules
2.53.459 Protein Adsorption
Web Of Science research areas
Chemistry, Multidisciplinary
Chemistry, Physical
Materials Science, Multidisciplinary
Nanoscience & Nanotechnology
Physics, Applied
Physics, Condensed Matter
ESI research areas
Materials Science

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