A Two-way Messaging System to Enhance Antiretroviral Adherence

Peter J Dunbar; David Madigan; Lisa A Grohskopf; Debra Revere; Jane Woodward; James Minstrell; Pamela A Frick; Jane M Simoni; Thomas M Hooton

doi:10.1197/jamia.M1047

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A Two-way Messaging System to Enhance Antiretroviral Adherence

Journal article

Open access

A Two-way Messaging System to Enhance Antiretroviral Adherence

Peter J Dunbar, David Madigan, Lisa A Grohskopf, Debra Revere, Jane Woodward, James Minstrell, Pamela A Frick, Jane M Simoni and Thomas M Hooton

Journal of the American Medical Informatics Association : JAMIA, Vol.10(1), pp.11-15

2003

DOI: https://doi.org/10.1197/jamia.M1047

PMCID: PMC150355

PMID: 12509353

Abstract

The Practice of Informatics

Failure to adhere to complex antiretroviral regimens can lead to resistance and treatment failure among HIV-positive persons. In this study of the feasibility of an automated two-way messaging system to improve adherence, participants received multiple short daily messages designed to remind, educate, encourage adherence, and solicit responses concerning side effects and self-reported adherence. Twenty-five participants remained in the study for a median of 208 days, receiving 17,440 messages and replying to 14,677 (84%). Participants reported missing one or more doses on 36% of 743 queries and reported medication side effects on 26% of 729 queries. Participants expressed high satisfaction with the messaging system and reported that it helped with medication adherence. The study suggests that it is feasible to use an automated wireless two-way messaging system to communicate with HIV-positive patients over an extended period of time.

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Citation topics: 1 Clinical & Life Sciences; 1.66 HIV; 1.66.11 HIV Prevalence & Prophylaxis
Web Of Science research areas: Computer Science, Information Systems; Computer Science, Interdisciplinary Applications; Health Care Sciences & Services; Information Science & Library Science; Medical Informatics
ESI research areas: Social Sciences, general

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Details

Title: A Two-way Messaging System to Enhance Antiretroviral Adherence
Creators: Peter J Dunbar - Affiliations of the authors: Department of Anesthesiology, University of Washington, Seattle, Washington (PJD); Department of Statistics, University of Washington, Seattle, Washington (DM); Department of Medicine, University of Washington, Seattle, Washington (LAG, TMH); Department of Health Sciences Libraries, University of Washington, Seattle, Washington (DR); Department of Pharmacy, University of Washington, Seattle, Washington (JW, PAF); Talaria, Inc., Seattle, Washington (JM); Department of Psychology, University of Washington, Seattle, Washington (JMS)
David Madigan - Affiliations of the authors: Department of Anesthesiology, University of Washington, Seattle, Washington (PJD); Department of Statistics, University of Washington, Seattle, Washington (DM); Department of Medicine, University of Washington, Seattle, Washington (LAG, TMH); Department of Health Sciences Libraries, University of Washington, Seattle, Washington (DR); Department of Pharmacy, University of Washington, Seattle, Washington (JW, PAF); Talaria, Inc., Seattle, Washington (JM); Department of Psychology, University of Washington, Seattle, Washington (JMS)
Lisa A Grohskopf - Affiliations of the authors: Department of Anesthesiology, University of Washington, Seattle, Washington (PJD); Department of Statistics, University of Washington, Seattle, Washington (DM); Department of Medicine, University of Washington, Seattle, Washington (LAG, TMH); Department of Health Sciences Libraries, University of Washington, Seattle, Washington (DR); Department of Pharmacy, University of Washington, Seattle, Washington (JW, PAF); Talaria, Inc., Seattle, Washington (JM); Department of Psychology, University of Washington, Seattle, Washington (JMS)
Debra Revere - Affiliations of the authors: Department of Anesthesiology, University of Washington, Seattle, Washington (PJD); Department of Statistics, University of Washington, Seattle, Washington (DM); Department of Medicine, University of Washington, Seattle, Washington (LAG, TMH); Department of Health Sciences Libraries, University of Washington, Seattle, Washington (DR); Department of Pharmacy, University of Washington, Seattle, Washington (JW, PAF); Talaria, Inc., Seattle, Washington (JM); Department of Psychology, University of Washington, Seattle, Washington (JMS)
Jane Woodward - Affiliations of the authors: Department of Anesthesiology, University of Washington, Seattle, Washington (PJD); Department of Statistics, University of Washington, Seattle, Washington (DM); Department of Medicine, University of Washington, Seattle, Washington (LAG, TMH); Department of Health Sciences Libraries, University of Washington, Seattle, Washington (DR); Department of Pharmacy, University of Washington, Seattle, Washington (JW, PAF); Talaria, Inc., Seattle, Washington (JM); Department of Psychology, University of Washington, Seattle, Washington (JMS)
James Minstrell - Affiliations of the authors: Department of Anesthesiology, University of Washington, Seattle, Washington (PJD); Department of Statistics, University of Washington, Seattle, Washington (DM); Department of Medicine, University of Washington, Seattle, Washington (LAG, TMH); Department of Health Sciences Libraries, University of Washington, Seattle, Washington (DR); Department of Pharmacy, University of Washington, Seattle, Washington (JW, PAF); Talaria, Inc., Seattle, Washington (JM); Department of Psychology, University of Washington, Seattle, Washington (JMS)
Pamela A Frick - Affiliations of the authors: Department of Anesthesiology, University of Washington, Seattle, Washington (PJD); Department of Statistics, University of Washington, Seattle, Washington (DM); Department of Medicine, University of Washington, Seattle, Washington (LAG, TMH); Department of Health Sciences Libraries, University of Washington, Seattle, Washington (DR); Department of Pharmacy, University of Washington, Seattle, Washington (JW, PAF); Talaria, Inc., Seattle, Washington (JM); Department of Psychology, University of Washington, Seattle, Washington (JMS)
Jane M Simoni - Affiliations of the authors: Department of Anesthesiology, University of Washington, Seattle, Washington (PJD); Department of Statistics, University of Washington, Seattle, Washington (DM); Department of Medicine, University of Washington, Seattle, Washington (LAG, TMH); Department of Health Sciences Libraries, University of Washington, Seattle, Washington (DR); Department of Pharmacy, University of Washington, Seattle, Washington (JW, PAF); Talaria, Inc., Seattle, Washington (JM); Department of Psychology, University of Washington, Seattle, Washington (JMS)
Thomas M Hooton - Affiliations of the authors: Department of Anesthesiology, University of Washington, Seattle, Washington (PJD); Department of Statistics, University of Washington, Seattle, Washington (DM); Department of Medicine, University of Washington, Seattle, Washington (LAG, TMH); Department of Health Sciences Libraries, University of Washington, Seattle, Washington (DR); Department of Pharmacy, University of Washington, Seattle, Washington (JW, PAF); Talaria, Inc., Seattle, Washington (JM); Department of Psychology, University of Washington, Seattle, Washington (JMS)
Publication Details: Journal of the American Medical Informatics Association : JAMIA, Vol.10(1), pp.11-15
Publisher: American Medical Informatics Association
Academic Unit: Miller School of Medicine
Language: English
Resource Type: Journal article
PMID: 12509353
PMCID: PMC150355
Record Identifier: 991031560337402976