A propitious time for initiating clinical trials in patients with heart failure with reduced ejection fraction and an estimated glomerular filtration rate <30 mL/min with an mineralocorticoid receptor antagonist and a K+ binder: 'the forbidden fruit'

Murray Epstein; Bertram C Pitt

doi:10.1093/eurheartj/ehw222

$A propitious time for initiating clinical trials in patients with heart failure with reduced ejection fraction and an estimated glomerular filtration rate <30 mL/min with an mineralocorticoid receptor antagonist and a K+ binder: 'the forbidden fruit'$

Journal article

Peer reviewed

A propitious time for initiating clinical trials in patients with heart failure with reduced ejection fraction and an estimated glomerular filtration rate <30 mL/min with an mineralocorticoid receptor antagonist and a K+ binder: 'the forbidden fruit'

Murray Epstein and Bertram C Pitt

European heart journal, Vol.37(41), pp.3130-3134

2016-11-01

DOI: https://doi.org/10.1093/eurheartj/ehw222

PMID: 27354056

Abstract

Glomerular Filtration Rate - physiology

Heart Failure - complications

Heart Failure - drug therapy

Heart Failure - epidemiology

Heart Failure - physiopathology

Humans

Mineralocorticoid Receptor Antagonists - therapeutic use

Monitoring, Physiologic

Patient Selection

Randomized Controlled Trials as Topic

Renal Insufficiency, Chronic - complications

Renal Insufficiency, Chronic - drug therapy

Renal Insufficiency, Chronic - epidemiology

Renal Insufficiency, Chronic - physiopathology

Stroke Volume - physiology

Metrics

3 Record Views

3 Times Cited - Web of Science

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Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.55 Urology & Nephrology - General; 1.55.352 Chronic Kidney Disease
Web Of Science research areas: Cardiac & Cardiovascular Systems
ESI research areas: Clinical Medicine

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Source: InCites

Details

Title: A propitious time for initiating clinical trials in patients with heart failure with reduced ejection fraction and an estimated glomerular filtration rate <30 mL/min with an mineralocorticoid receptor antagonist and a K+ binder: 'the forbidden fruit'
Creators: Murray Epstein - University of Miami
Bertram C Pitt - University of Michigan–Ann Arbor
Publication Details: European heart journal, Vol.37(41), pp.3130-3134
Academic Unit: Benefits - Other; Human Resources
Language: English
Resource Type: Journal article
PMID: 27354056
Record Identifier: 991031740153202976