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AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges
Journal article   Open access  Peer reviewed

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

Matthew R Gardner, Lisa M Kattenhorn, Hema R Kondur, Markus von Schaewen, Tatyana Dorfman, Jessica J Chiang, Kevin G Haworth, Julie M Decker, Michael D Alpert, Charles C Bailey, …
Nature (London), Vol.519(7541), pp.87-91
2015-03-05
PMID: 25707797

Abstract

CD4 Antigens - immunology Dependovirus - genetics Genetic Therapy Immunoglobulins - immunology AIDS Vaccines - immunology CCR5 Receptor Antagonists - immunology Male Neutralization Tests Macaca mulatta Immunoglobulins - genetics Virus Internalization Simian Acquired Immunodeficiency Syndrome - prevention & control Antibodies, Neutralizing - immunology HIV-1 - immunology Receptors, CCR5 - metabolism Simian Acquired Immunodeficiency Syndrome - virology Animals HIV Antibodies - immunology Simian Acquired Immunodeficiency Syndrome - immunology HIV-2 - immunology AIDS Vaccines - genetics Female CD4 Antigens - genetics Simian Immunodeficiency Virus - immunology
url
https://doi.org/10.1038/nature14264View
Published (Version of record) Open

InCites Highlights

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Collaboration types
Domestic collaboration
International collaboration
Citation topics
1 Clinical & Life Sciences
1.66 HIV
1.66.46 HIV-1
Web Of Science research areas
Virology
ESI research areas
Microbiology

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#3 Good Health and Well-Being

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