Abstract
Background: Women with congenital heart disease (CHD) have an increased risk of complications during pregnancy including heart failure (HF), arrhythmias, and thromboembolic events (TEC). In 2010, Drenthen proposed a maternal risk score (MRS) to predict maternal complications, but this score has yet to be verified in a prospective population. Methods: We reviewed 78 pregnancies in 70 women, mean age 26.97 ± 5.71 years (range 17.12 - 41.8). CHD defect classification was simple in 5 (6.4%), moderate in 48 (61.5%), complex in 20 (25.6%), and other in 5 (6.4%) with mean MRS of 1.45 (range 0- 9). Results: Maternal cardiac complications defined as clinically significant arrhythmia, HF, or TEC occurred in 17 pregnancies (28.8%). Risk distribution and maternal complications rates are shown in the table. There was a statistically significant trend towards a higher rate of adverse cardiac events with a higher MRS (p = 0.023). All complications in two lowest risk categories (0-1.50) were arrhythmias. A logistic model...