Are Steroids a Beneficial Adjunctive Therapy in the Immunosuppressed Patient with Herpes Simplex Virus Encephalitis?

Karlo J Lizarraga; Lucien C Alexandre; Ciro Ramos-Estebanez; Amedeo Merenda

doi:10.1159/000350572

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Are Steroids a Beneficial Adjunctive Therapy in the Immunosuppressed Patient with Herpes Simplex Virus Encephalitis?

Journal article

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Peer reviewed

Are Steroids a Beneficial Adjunctive Therapy in the Immunosuppressed Patient with Herpes Simplex Virus Encephalitis?

Karlo J Lizarraga, Lucien C Alexandre, Ciro Ramos-Estebanez and Amedeo Merenda

Case reports in neurology, Vol.5(1), pp.52-55

2013-03-21

DOI: https://doi.org/10.1159/000350572

PMCID: PMC3635685

PMID: 23626565

Abstract

Immunosuppression

Corticosteroids

Published online

March, 2013

Herpes simplex virus encephalitis

Few reports describe the reactivation of latent herpes simplex virus causing encephalitis (HSVE) in patients undergoing brain radiation therapy and a concomitant steroid regimen. The role for steroid use in the treatment of patients with HSVE has not been fully elucidated. We report the case of a female patient immunosuppressed by steroids and brain radiation who developed HSVE and responded to acyclovir and dexamethasone.

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Details

Title: Are Steroids a Beneficial Adjunctive Therapy in the Immunosuppressed Patient with Herpes Simplex Virus Encephalitis?
Creators: Karlo J Lizarraga - Neurocritical Care Division, Department of Neurology, Miller School of Medicine, University of Miami, Miami, Fla., USA
Lucien C Alexandre - Neurocritical Care Division, Department of Neurology, Miller School of Medicine, University of Miami, Miami, Fla., USA
Ciro Ramos-Estebanez - Neurocritical Care Division, Department of Neurology, Miller School of Medicine, University of Miami, Miami, Fla., USA
Amedeo Merenda - Neurocritical Care Division, Department of Neurology, Miller School of Medicine, University of Miami, Miami, Fla., USA
Publication Details: Case reports in neurology, Vol.5(1), pp.52-55
Publisher: S. Karger AG; Allschwilerstrasse 10, P.O. Box · Postfach · Case postale, CH–4009, Basel, Switzerland · Schweiz · Suisse, Phone: +41 61 306 11 11, Fax: +41 61 306 12 34, karger@karger.ch
Academic Unit: Miller School of Medicine; UMMG Department of Neurology; UMMG Dept of Neurology - Neurocritical Care Div
Language: English
Resource Type: Journal article
PMID: 23626565
PMCID: PMC3635685
Record Identifier: 991031577128302976