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Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint
Journal article   Open access

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint

A.M. Staffaroni, L. Bajorek, K.B. Casaletto, Y. Cobigo, S.-Y.M. Goh, A. Wolf, H.W. Heuer, F.M. Elahi, P.A. Ljubenkov, R. Dever, …
Alzheimer's and Dementia, Vol.16(1), pp.11-21
2020
PMID: 31914230

Abstract

Biomarkers C9orf72 Protein Disease Progression Executive Function Female Frontotemporal Dementia Humans Longitudinal Studies Magnetic Resonance Imaging Male Middle Aged Mutation Neuropsychological Tests biological marker C9orf72 protein, human guanine nucleotide exchange C9orf72 adult Article brain size Clinical Dementia Rating cognition cognitive defect episodic memory executive function female follow up frontotemporal dementia functional disease human major clinical study male middle aged neuropsychological test neuropsychology nuclear magnetic resonance imaging priority journal working memory disease exacerbation executive function frontotemporal dementia genetics longitudinal study mutation physiology
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85065401051&doi=10.1016%2fj.jalz.2019.01.012&partnerID=40&md5=03fd8d443ca0d0c6d5132a14e5f82764View
url
https://doi.org/10.1016/j.jalz.2019.01.012View
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