Assessment of eye length changes in accommodation using dynamic extended-depth OCT

Yu-Cherng Chang; Keke Liu; Carolina de Freitas; Alex Pham; Florence Cabot; Siobhan Williams; Ethan Adre; Giovanni Gregori; Marco Ruggeri; Sonia H Yoo; Arthur Ho; Jean-Marie Parel; Fabrice Manns

doi:10.1364/BOE.8.002709

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Assessment of eye length changes in accommodation using dynamic extended-depth OCT

Journal article

Open access

Peer reviewed

Assessment of eye length changes in accommodation using dynamic extended-depth OCT

Yu-Cherng Chang, Keke Liu, Carolina de Freitas, Alex Pham, Florence Cabot, Siobhan Williams, Ethan Adre, Giovanni Gregori, Marco Ruggeri, Sonia H Yoo, …

Biomedical optics express, Vol.8(5), pp.2709-2719

2017-05-01

DOI: https://doi.org/10.1364/BOE.8.002709

PMCID: PMC5480507

PMID: 28663900

Abstract

(330.5370) Physiological optics

(330.7327) Visual optics, ophthalmic instrumentation

(170.4500) Optical coherence tomography

(330.7322) Visual optics, accommodation

It has been suggested that accommodation induces increases in axial eye length which could contribute to the development of myopia. However, it is debated whether changes in eye length occur during accommodation as the degree of change varies widely across literature. In this study, an extended-depth optical coherence tomography (OCT) system that provides dynamic whole eye biometry was utilized to assess changes in lens thickness (LT) and axial eye length (AEL) in young subjects responding to step disaccommodation stimuli of amplitude 2D, 4D, and 6D. The decrease in lens thickness with disaccommodation was strongly correlated with stimulus amplitude. No statistically significant changes in AEL during accommodation were observed.

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Collaboration types: Industry collaboration; Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.36 Ophthalmology; 1.36.813 Myopia
Web Of Science research areas: Biochemical Research Methods; Optics; Radiology, Nuclear Medicine & Medical Imaging
ESI research areas: Biology & Biochemistry

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Details

Title: Assessment of eye length changes in accommodation using dynamic extended-depth OCT
Creators: Yu-Cherng Chang - Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Keke Liu - Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Carolina de Freitas - Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Alex Pham - Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Florence Cabot - Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Siobhan Williams - Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Ethan Adre - Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Giovanni Gregori - Quantitative Imaging Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Marco Ruggeri - Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Sonia H Yoo - Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Arthur Ho - Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Jean-Marie Parel - Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Fabrice Manns - Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
Publication Details: Biomedical optics express, Vol.8(5), pp.2709-2719
Publisher: Optical Society of America
Grant note: Henri and Flore Lesieur Foundation Florida Lions Eye Bank Research to Prevent Blindness (RPB) Australian Federal Government Cooperative Research Centre Drs. Raksha Urs and Aaron Furtado; Karl R. Olsen, MD and Martha E. Hildebrandt, PhD 2R01EY14225; P30EY14801 / National Eye Institute (NEI)
Academic Unit: Miller School of Medicine; College of Engineering; UMMG Department of Ophthalmology; CoE - Biomedical Engineering
Language: English
Resource Type: Journal article
PMID: 28663900
PMCID: PMC5480507
Record Identifier: 991031576822802976