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Association of Interleukin 6 Receptor Variant With Cardiovascular Disease Effects of Interleukin 6 Receptor Blocking Therapy: A Phenome-Wide Association Study
Journal article   Open access  Peer reviewed

Association of Interleukin 6 Receptor Variant With Cardiovascular Disease Effects of Interleukin 6 Receptor Blocking Therapy: A Phenome-Wide Association Study

Tianxi Cai, Yichi Zhang, Yuk-Lam Ho, Nicholas Link, Jiehuan Sun, Jie Huang, Tianrun A Cai, Scott Damrauer, Yuri Ahuja, Jacqueline Honerlaw, …
JAMA cardiology, Vol.3(9), pp.849-857
2018-09
DOI: https://doi.org/10.1001/jamacardio.2018.2287
PMCID: PMC6233652
PMID: 30090940

Abstract

Online First Original Investigation Research
This phenome-wide association study assesses clinical associations between interleukin 6 receptor ( IL6R ) single-nucleotide polyporphisms and known IL6R drug effects and whether large biobanks and genetics can be used to assess potential beneficial and adverse effects of therapeutic agents with known pathways and related genes.
url
https://doi.org/10.1001/jamacardio.2018.2287View
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58 Times Cited - Web of Science

InCites Highlights

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.189 Genome Studies
1.189.455 Genome-Wide Association Studies
Web Of Science research areas
Cardiac & Cardiovascular Systems
ESI research areas
Clinical Medicine

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#3 Good Health and Well-Being

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