Abstract
This cross-sectional study investigates if a genetic risk score that comprised 12 primary open-angle glaucoma genetic risk variants is associated with age at disease diagnosis.
- Title
- Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis
- Creators
- Bao Jian Fan - Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear, BostonJessica Cooke Bailey - Institute for Computational Biology, Case Western Reserve University School of Medicine, Cleveland, OhioRob P Igo - Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OhioJae H Kang - Channing Division of Network Medicine, Brigham and Women’s Hospital/Harvard Medical School, Boston, MassachusettsTahani Boumenna - Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear, BostonMurray H Brilliant - Marshfield Clinic Research Institute, Marshfield, WisconsinDonald L Budenz - Department of Ophthalmology, University of North Carolina, Chapel HillJohn H Fingert - Department of Ophthalmology, University of Iowa, College of Medicine, Iowa CityTerry Gaasterland - Scripps Genome Center, University of California at San Diego, San DiegoDouglas Gaasterland - The Emmes Corporation, Rockville, MarylandMichael A Hauser - Department of Ophthalmology, Duke University Medical Center, Durham, North CarolinaPeter Kraft - Department of Epidemiology, Harvard T. H. Chan School of Public Health, Harvard Medical School, Boston, MassachusettsRichard K Lee - Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FloridaPaul R Lichter - Department of Ophthalmology and Visual Sciences, University of Michigan, Ann ArborYutao Liu - Department of Cellular Biology and Anatomy, Augusta University, Augusta, GeorgiaSyoko E Moroi - Department of Ophthalmology and Visual Sciences, University of Michigan, Ann ArborJonathan S Myers - Wills Eye Hospital, Philadelphia, PennsylvaniaMargaret A Pericak-Vance - Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FloridaAnthony Realini - Department of Ophthalmology, WVU Eye Institute, Morgantown, West VirginiaDouglas J Rhee - Department of Ophthalmology, Case Western Reserve University School of Medicine, Cleveland, OhioJulia E Richards - Department of Ophthalmology and Visual Sciences, University of Michigan, Ann ArborRobert Ritch - Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New YorkJoel S Schuman - Department of Ophthalmology, NYU Langone Medical Center, NYU School of Medicine, New York, New YorkWilliam K Scott - Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FloridaKuldev Singh - Department of Ophthalmology, Stanford University, Palo Alto, CaliforniaArthur J Sit - Department of Ophthalmology, Mayo Clinic, Rochester, MinnesotaDouglas Vollrath - Department of Genetics, Stanford University, Palo Alto, CaliforniaRobert N Weinreb - Department of Ophthalmology, Hamilton Glaucoma Center and Shiley Eye Institute, University of California at San Diego, La JollaGadi Wollstein - Department of Ophthalmology, NYU Langone Medical Center, NYU School of Medicine, New York, New YorkDonald J Zack - Wilmer Eye Institute, Johns Hopkins University Hospital, Baltimore, MarylandJonathan L Haines - Institute for Computational Biology, Case Western Reserve University School of Medicine, Cleveland, OhioLouis R Pasquale - Department of Ophthalmology, Icahn School of Medicine, Mount Sinai Hospital, New YorkJaney L Wiggs - Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear, Boston
- Publication Details
- JAMA ophthalmology, Vol.137(10), pp.1190-1194
- Publisher
- American Medical Association
- Grant note
- National Institutes of Health National Human Genome Research Institute National Eye Institute
- Academic Unit
- Miller School of Medicine; John P. Hussman Institute for Human Genomics; UMMG Department of Ophthalmology; UMMG Dept of Human Genetics - Clinical and Translational Genetics; UMMG Dept of Human Genetics (Dr. John T. Macdonald Foundation)
- Language
- English
- Resource Type
- Journal article
- PMID
- 31436842
- Record Identifier
- 991031577446102976