Abstract
•CAPNONs are extremely rare lesions and their etiology remains largely unknown.•These lesions may mimic more common pathologies such as cavernomas radiographically.•Proper CAPNON diagnosis necessitates histopathological investigation.•Surgical intervention is typically curative for intra-axial CAPNONs presenting with seizures.
Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare benign lesions that can arise anywhere within the central nervous system. The etiology of these lesions remains unknown and diagnosis is made on pathohistological analysis. We present the case of a 35-year-old male patient with a history of epilepsy since childhood who was evaluated for refractory seizures. MRI revealed a small lesion in the left-posterior temporal lobe suspected to be a cavernoma. A gross total resection of the lesion was achieved via a left temporal craniotomy and pathological analysis revealed CAPNON. At 6 months follow-up, the patient remained neurologically intact and his seizures had ceased.