Sign in
Calcium ion release in mechanically disrupted heart cells
Journal article   Peer reviewed

Calcium ion release in mechanically disrupted heart cells

W G Kerrick and P M Best
Science (American Association for the Advancement of Science), Vol.183(4123), pp.435-437
1974-02-01
PMID: 4203025

Abstract

Sodium - pharmacology Animals Calcium - pharmacology Calcium - metabolism Myocardium - metabolism Caffeine - pharmacology Rats Sarcoplasmic Reticulum - metabolism Stimulation, Chemical Chelating Agents Haplorhini Myocardium - cytology
In cardiac muscle fibers which have had their sarcolemma disrupted intracellular stores of calcium ions can be released by the same chemical stimuli which cause their release from the sarcoplasmic reticulum of skinned skeletal muscle fibers. These stimuli are increases in calcium or caffeine concentrations and substitution of chloride for propionate or sodium for potassium in solutions bathing the fibers.

Metrics

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

undefined

Source: InCites

Details