Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

James O MCNAMARA; Eran R ANDRECHEK; YONG YONG WANG; Kristi D VILES; Rachel E REMPEL; Eli GILBOA; Bruce A SULLENGER; Paloma H GIANGRANDE

doi:10.1038/nbt1223

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Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

Journal article

Peer reviewed

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

James O MCNAMARA, Eran R ANDRECHEK, YONG YONG WANG, Kristi D VILES, Rachel E REMPEL, Eli GILBOA, Bruce A SULLENGER and Paloma H GIANGRANDE

Nature biotechnology, Vol.24(8), pp.1005-1015

2006

DOI: https://doi.org/10.1038/nbt1223

PMID: 16823371

Abstract

Fundamental and applied biological sciences. Psychology

Biotechnology

Chemotherapy

Health. Pharmaceutical industry

Industrial applications and implications. Economical aspects

Pharmacology. Drug treatments

Biological and medical sciences

Medical sciences

Gene therapy

Antineoplastic agents

Metrics

18 Record Views

814 Times Cited - Web of Science

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InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Citation topics: 2 Chemistry; 2.145 Biosensors; 2.145.243 Aptamer
Web Of Science research areas: Biotechnology & Applied Microbiology
ESI research areas: Biology & Biochemistry

UN Sustainable Development Goals (SDGs)

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Source: InCites

Details

Title: Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
Creators: James O MCNAMARA - Duke Center for Translational Research, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States
Eran R ANDRECHEK - Duke Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina 27710, United States
YONG YONG WANG - Duke Center for Translational Research, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States
Kristi D VILES - Duke Center for Translational Research, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States
Rachel E REMPEL - Duke Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina 27710, United States
Eli GILBOA - Duke Center for Translational Research, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States
Bruce A SULLENGER - Duke Center for Translational Research, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States
Paloma H GIANGRANDE - Duke Center for Translational Research, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, United States
Publication Details: Nature biotechnology, Vol.24(8), pp.1005-1015
Publisher: Nature; New York, NY
Academic Unit: Miller School of Medicine; Microbiology and Immunology Research
Language: English
Resource Type: Journal article
PMID: 16823371
Record Identifier: 991031562082202976