Abstract
Cellulite is a common esthetic concern for a large majority of post-pubertal women usually regardless of body habitus and body mass index. Previous therapies have been largely ineffective or lack durable responses. Cadaveric studies have elucidated anatomic differences in the fibrous septae within the subcutaneous tissue between men and women. The orientation of the septae in women may explain the appearance of cellulite. Treatments targeting the fibrous septae have proven to be most successful and long-lasting. The aim of this article is to describe the latest updates in cellulite treatment, specifically vacuum-assisted tissue-stabilized guided subcision, targeted verifiable subcision, rapid acoustic pulse, and enzymatic treatment with collagenase clostridium histolyticum-aaes.