Abstract
Approximately 5 million Americans live with mild cognitive impairment (MCI) and Alzheimer disease (AD). Age adds a layer of complexity to disease management not present with younger adults, as older adults have a greater likelihood of multiple chronic conditions that can diminish their capacity to function independently. Chronic disease burden increases risk of MCI, while certain lifestyle factors may reduce MCI risk.(1) This implies that preventive strategies for MCI may need to begin in midlife and persist throughout late life.