Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Adam C NAJ; Gyungah JUN; Eric B LARSON; Thomas D BIRD; Bradley F BOEVE; Neill R GRAFF-RADFORD; Philip L.de JAGER; Denis EVANS; Julie A SCHNEIDER; Minerva M CARRASQUILLO; Nilufer ERTEKIN-TANER; Steven G YOUNKIN; Gary W BEECHAM; Carlos CRUCHAGA; John S. K KAUWE; Petra NOWOTNY; Patricia KRAMER; John HARDY; Matthew J HUENTELMAN; Amanda J MYERS; Michael M BARMADA; F. Yesim DEMIRCI; Clinton T BALDWIN; Li-San WANG; Robert C GREEN; Ekaterina ROGAEVA; Peter STGEORGE-HYSLOP; Steven EARNOLD; Robert BARBER; Thomas BEACH; Eileen H BIGIO; James D BOWEN; Adam BOXER; James R BURKE; BADRI NARAYAN BADRI NARAYAN VARDARAJAN; Nigel J CAIRNS; Chriss CARLSON; Regina MCARNEY; Stevenl CARROLL; Helena CCHUI; David G CLARK; Jason CORNEVEAUX; Carl W COTMAN; Jeffrey L CUMMINGS; Charles DECARLI; Jacqueline BUROS; Steven T DEKOSKY; Ramon DIAZ-ARRASTIA; Malcolm DICK; Dennis W DICKSON; William G ELLIS; Kelley M FABER; Kenneth B FALLON; Martin R FARLOW; Steven FERRIS; Matthew P FROSCH; Paul J GALLINS; Joseph D BUXBAUM; Gail P JARVIK; Paul K CRANE

doi:10.1038/ng.801

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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Adam C NAJ, Gyungah JUN, Eric B LARSON, Thomas D BIRD, Bradley F BOEVE, Neill R GRAFF-RADFORD, Philip L.de JAGER, Denis EVANS, Julie A SCHNEIDER, Minerva M CARRASQUILLO, …

Nature genetics, Vol.43(5), pp.436-441

2011

DOI: https://doi.org/10.1038/ng.801

PMID: 21460841

Abstract

Fundamental and applied biological sciences. Psychology

Neurology

Organic mental disorders. Neuropsychology

Psychology. Psychoanalysis. Psychiatry

Adult and adolescent clinical studies

Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases

Psychopathology. Psychiatry

Biological and medical sciences

Genetics of eukaryotes. Biological and molecular evolution

Medical sciences

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.52 Neurodegenerative Diseases; 1.52.57 Alzheimer's Disease
Web Of Science research areas: Genetics & Heredity
ESI research areas: Molecular Biology & Genetics

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Title: Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
Creators: Adam C NAJ - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Gyungah JUN - Department of Biostatistics, Boston University, Boston, Massachusetts, United States
Eric B LARSON - Group Health Research Institute, Seattle, Washington, United States
Thomas D BIRD - Department of Neurology, University of Washington, Seattle, Washington, United States
Bradley F BOEVE - Department of Neurology, Mayo Clinic, Rochester, Minnesota, United States
Neill R GRAFF-RADFORD - Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States
Philip L.de JAGER - Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts, United States
Denis EVANS - Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States
Julie A SCHNEIDER - Department of Pathology (Neuropathology), Rush University Medical Center, Chicago, Illinois, United States
Minerva M CARRASQUILLO - Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States
Nilufer ERTEKIN-TANER - Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States
Steven G YOUNKIN - Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States
Gary W BEECHAM - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Carlos CRUCHAGA - Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration, United States
John S. K KAUWE - Washington University School of Medicine, St. Louis, Missouri, United States
Petra NOWOTNY - Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration, United States
Patricia KRAMER - Department of Biology, Brigham Young University, Provo, Utah, United States
John HARDY - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Matthew J HUENTELMAN - Department of Biostatistics, Boston University, Boston, Massachusetts, United States
Amanda J MYERS - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Michael M BARMADA - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
F. Yesim DEMIRCI - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Clinton T BALDWIN - Department of Medicine (Genetics Program), Boston University, Boston, Massachusetts, United States
Li-San WANG - Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States
Robert C GREEN - Department of Medicine (Genetics Program), Boston University, Boston, Massachusetts, United States
Ekaterina ROGAEVA - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Peter STGEORGE-HYSLOP - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Steven EARNOLD - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Robert BARBER - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Thomas BEACH - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Eileen H BIGIO - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
James D BOWEN - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Adam BOXER - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
James R BURKE - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
BADRI NARAYAN BADRI NARAYAN VARDARAJAN - Department of Medicine (Genetics Program), Boston University, Boston, Massachusetts, United States
Nigel J CAIRNS - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Chriss CARLSON - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Regina MCARNEY - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Stevenl CARROLL - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Helena CCHUI - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
David G CLARK - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Jason CORNEVEAUX - Department of Biostatistics, Boston University, Boston, Massachusetts, United States
Carl W COTMAN - Department of Ophthalmology, Boston University, Boston, Massachusetts, United States
Jeffrey L CUMMINGS - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Charles DECARLI - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Jacqueline BUROS - Department of Medicine (Genetics Program), Boston University, Boston, Massachusetts, United States
Steven T DEKOSKY - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Ramon DIAZ-ARRASTIA - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Malcolm DICK - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Dennis W DICKSON - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
William G ELLIS - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Kelley M FABER - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Kenneth B FALLON - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Martin R FARLOW - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Steven FERRIS - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Matthew P FROSCH - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Paul J GALLINS - The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States
Joseph D BUXBAUM - Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, United States
Gail P JARVIK - Department of Genome Sciences, University of Washington, Seattle, Washington, United States
Paul K CRANE - Department of Medicine, University of Washington, Seattle, Washington, United States
Publication Details: Nature genetics, Vol.43(5), pp.436-441
Publisher: Nature Publishing Group; New York, NY
Academic Unit: Miller School of Medicine; Cell Biology Research; John P. Hussman Institute for Human Genomics; UMMG Department of Public Health Sciences Research; UMMG Dept of Human Genetics (Dr. John T. Macdonald Foundation)
Language: English
Resource Type: Journal article
PMID: 21460841
Record Identifier: 991031560156602976