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Correct axonal regeneration after target cell removal in the central nervous system of the leech
Journal article   Peer reviewed

Correct axonal regeneration after target cell removal in the central nervous system of the leech

K J Muller and S A Scott
Science (American Association for the Advancement of Science), Vol.206(4414), pp.87-89
1979-10-05
PMID: 482931

Abstract

Central Nervous System - growth & development Central Nervous System - physiology Animals Synapses - physiology Cell Communication Nerve Regeneration Leeches - physiology
The unique target neuron of a severed axon in the leech was selectively eliminated by intracellular injection of protease. In the absence of the target, the severed axon regenerated normally along its original pathway to the usual site of synapse, where it stopped growing without forming alternative connections.

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