- Title
- DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome
- Creators
- Hans Richter - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandAlexander L Satz - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandMarc Bedoucha - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandBernd Buettelmann - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandAnn C Petersen - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandAnja Harmeier - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandRicardo Hermosilla - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandRemo Hochstrasser - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandDominique Burger - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandBernard Gsell - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandRodolfo Gasser - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandSylwia Huber - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandMelanie N Hug - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandBuelent Kocer - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandBernd Kuhn - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandMartin Ritter - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandMarkus G Rudolph - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandFranziska Weibel - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, Switzerland, Ridgeline Therapeutics GmbH, Basel 4070, SwitzerlandJudith Molina-David - Katz Family Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, Florida 33136, United States, Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida 33136, United StatesJin-Ju Kim - Katz Family Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, Florida 33136, United States, Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida 33136, United StatesJavier Varona Santos - Katz Family Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, Florida 33136, United States, Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida 33136, United StatesMartine Stihle - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandGuy J Georges - Roche Pharma Research and Early Development, Roche Innovation Center, Munich 82377, GermanyR. Daniel Bonfil - Department of Pathology, College of Medical Sciences, Nova Southeastern University, Fort Lauderdale, Florida 33328, United StatesRafael Fridman - Department of Pathology, Wayne State University, Detroit, Michigan 48202, United StatesSabine Uhles - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, SwitzerlandSolange Moll - University Hospital of Geneva, 1205 Geneva, SwitzerlandChristian Faul - University of Alabama at Birmingham, Birmingham, Alabama 35294, United StatesAlessia Fornoni - Katz Family Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, Florida 33136, United StatesMarco Prunotto - Roche Pharma Research and Early Development, Roche Innovation Center, Basel 4070, Switzerland, Office of Innovation, Immunology, Infectious Diseases & Ophthalmology (I2O), Roche and Genentech Late Stage Development, Basel 4070, Switzerland
- Publication Details
- ACS chemical biology, Vol.14(1), pp.37-49
- Academic Unit
- Miller School of Medicine; Peggy and Harold Katz Family Drug Discovery Center
- Language
- English
- Resource Type
- Journal article
- PMID
- 30452219
- PMCID
- PMC6343110
- Record Identifier
- 991031577271002976
Journal article
DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome
ACS chemical biology, Vol.14(1), pp.37-49
2019-01-18
PMCID: PMC6343110
PMID: 30452219
Metrics
21 Record Views
InCites Highlights
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.96 Cell Biology
- 1.96.2264 NM23
- Web Of Science research areas
- Biochemistry & Molecular Biology
- ESI research areas
- Biology & Biochemistry
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Source: InCites