DWI Reversal Is Associated with Small Infarct Volume in Patients with TIA and Minor Stroke

N Asdaghi; B.C.V Campbell; K.S Butcher; J.I Coulter; J Modi; A Qazi; M Goyal; A.M Demchuk; S.B Coutts

doi:10.3174/ajnr.A3733

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DWI Reversal Is Associated with Small Infarct Volume in Patients with TIA and Minor Stroke

Journal article

Open access

Peer reviewed

DWI Reversal Is Associated with Small Infarct Volume in Patients with TIA and Minor Stroke

N Asdaghi, B.C.V Campbell, K.S Butcher, J.I Coulter, J Modi, A Qazi, M Goyal, A.M Demchuk and S.B Coutts

American journal of neuroradiology : AJNR, Vol.35(4), pp.660-666

2014-04

DOI: https://doi.org/10.3174/ajnr.A3733

PMID: 24335541

Abstract

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The implications of the reversal of DWI abnormalities in patients with TIA and minor strokes were assessed. Patients were imaged within 24 hours of symptoms and followed for 3 months and baseline and final infarct volumes were calculated using DWI and FLAIR, respectively. Over 55% of patients had DWI lesions and 37% had perfusion deficits. DWI reversal occurred in 6% of patients with lesion volume being considerably smaller than in those that did not reverse. Perfusion abnormalities were less common in reversible lesions as well. The authors concluded that DWI lesion reversal is uncommon and more likely with smaller lesions.

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.105 Strokes; 1.105.142 Stroke
Web Of Science research areas: Clinical Neurology; Neuroimaging; Radiology, Nuclear Medicine & Medical Imaging
ESI research areas: Neuroscience & Behavior

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Title: DWI Reversal Is Associated with Small Infarct Volume in Patients with TIA and Minor Stroke
Creators: N Asdaghi - From Departments of Clinical Neurosciences (N.A., J.I.C., A.Q., M.G., A.M.D., S.B.C.)
B.C.V Campbell - The Royal Melbourne Hospital (B.C.V.C.), University of Melbourne, Parkville, Victoria, Australia
K.S Butcher - From Departments of Clinical Neurosciences (N.A., J.I.C., A.Q., M.G., A.M.D., S.B.C.)
J.I Coulter - From Departments of Clinical Neurosciences (N.A., J.I.C., A.Q., M.G., A.M.D., S.B.C.)
J Modi - Radiology (J.M., M.G., A.M.D., S.B.C.)
A Qazi - From Departments of Clinical Neurosciences (N.A., J.I.C., A.Q., M.G., A.M.D., S.B.C.)
M Goyal - From Departments of Clinical Neurosciences (N.A., J.I.C., A.Q., M.G., A.M.D., S.B.C.)
A.M Demchuk - From Departments of Clinical Neurosciences (N.A., J.I.C., A.Q., M.G., A.M.D., S.B.C.)
S.B Coutts - From Departments of Clinical Neurosciences (N.A., J.I.C., A.Q., M.G., A.M.D., S.B.C.)
Publication Details: American journal of neuroradiology : AJNR, Vol.35(4), pp.660-666
Publisher: American Society of Neuroradiology
Academic Unit: Miller School of Medicine; UMMG Department of Neurology; UMMG Dept of Neurology - Stroke Div
Language: English
Resource Type: Journal article
PMID: 24335541
Record Identifier: 991031614497102976