Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS

We are extremely grateful to all individuals who agreed to donate their brains to research. This work was supported by the National Institutes of Health/National Institute on Aging (R01AG026251 and P50AG016574 to L.P.), the National Institutes of Health/National Institute of Neurological Disorders and Stroke (R21NS089979 to T.F.G. and K.B.B.; R21NS084528, R01NS088689 and R01NS077402 to L.P.; R01NS063964 to L.P. and C.D.L.; P01NS084974 to L.P., D.W.D., R.R. and K.B.B.), the National Institute of Environmental Health Sciences (R01ES20395 to L.P.), the Department of Defense (ALSRP AL130125 to L.P.), the Mayo Clinic Foundation (L.P.), the Mayo Clinic Center for Individualized Medicine (L.P. and K.B.B.), the ALS Association (K.B.B., L.P., M.P. and T.F.G.), the Robert Packard Center for ALS Research at Johns Hopkins (L.P.), Target ALS (L.P.), the ALS Association (Milton Safenowitz postdoctoral fellowships to V.V.B. and M.P.), the Canadian Institutes of Health Research (postdoctoral fellowship to V.V.B.), the Siragusa Foundation (Career Development Award for Young Investigators to V.V.B.), and the Robert and Clarice Smith & Abigail Van Buren Alzheimer's Disease Research Foundation (postdoctoral fellowship to V.V.B.). H.L. and M.E.M. are supported by the Mayo Clinic Center for Individualized Medicine and the Donors Cure Foundation.