DrugCentral 2018: an update

Oleg Ursu; Jayme Holmes; Cristian G Bologa; Jeremy J Yang; Stephen L Mathias; Vasileios Stathias; Dac-Trung Nguyen; Stephan Schürer; Tudor Oprea

doi:10.1093/nar/gky963

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Journal article

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Peer reviewed

DrugCentral 2018: an update

Oleg Ursu, Jayme Holmes, Cristian G Bologa, Jeremy J Yang, Stephen L Mathias, Vasileios Stathias, Dac-Trung Nguyen, Stephan Schürer and Tudor Oprea

Nucleic acids research, Vol.47(D1), pp.D963-D970

2019-01-08

DOI: https://doi.org/10.1093/nar/gky963

PMCID: PMC6323925

PMID: 30371892

Abstract

Databases, Pharmaceutical

Pharmaceutical Preparations - classification

Drug Approval - statistics & numerical data

Proteins - classification

Gene Expression - drug effects

Drug-Related Side Effects and Adverse Reactions

DrugCentral is a drug information resource (http://drugcentral.org) open to the public since 2016 and previously described in the 2017 Nucleic Acids Research Database issue. Since the 2016 release, 103 new approved drugs were updated. The following new data sources have been included: Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS), FDA Orange Book information, L1000 gene perturbation profile distance/similarity matrices and estimated protonation constants. New and existing entries have been updated with the latest information from scientific literature, drug labels and external databases. The web interface has been updated to display and query new data. The full database dump and data files are available for download from the DrugCentral website.

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Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.54 Molecular & Cell Biology - Genetics; 1.54.79 Gene Expression Data
Web Of Science research areas: Biochemistry & Molecular Biology
ESI research areas: Biology & Biochemistry

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Details

Title: DrugCentral 2018: an update
Creators: Oleg Ursu - Translational Informatics Division, Department of Internal Medicine, The University of New Mexico Health Science Center, Albuquerque, NM 87131, USA
Jayme Holmes - Translational Informatics Division, Department of Internal Medicine, The University of New Mexico Health Science Center, Albuquerque, NM 87131, USA
Cristian G Bologa - Translational Informatics Division, Department of Internal Medicine, The University of New Mexico Health Science Center, Albuquerque, NM 87131, USA
Jeremy J Yang - Translational Informatics Division, Department of Internal Medicine, The University of New Mexico Health Science Center, Albuquerque, NM 87131, USA
Stephen L Mathias - Translational Informatics Division, Department of Internal Medicine, The University of New Mexico Health Science Center, Albuquerque, NM 87131, USA
Vasileios Stathias - Center for Computational Science, Miller School of Medicine, University of Miami, Coral Gables, FL 33146, USA
Dac-Trung Nguyen - National Center for Advancing Translational Science, 9800 Medical Center Drive, Rockville, MD 20850, USA
Stephan Schürer - Center for Computational Science, Miller School of Medicine, University of Miami, Coral Gables, FL 33146, USA
Tudor Oprea - Translational Informatics Division, Department of Internal Medicine, The University of New Mexico Health Science Center, Albuquerque, NM 87131, USA
Publication Details: Nucleic acids research, Vol.47(D1), pp.D963-D970
Publisher: England
Grant note: U24 CA224370 / NCI NIH HHS U24 TR002278 / NCATS NIH HHS
Academic Unit: Miller School of Medicine; Molecular and Cellular Pharmacology Research
Language: English
Resource Type: Journal article
PMID: 30371892
PMCID: PMC6323925
Record Identifier: 991031577275102976