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Electrodiffusion Model Simulation of Ionic Channels: 1D Simulations
Journal article   Peer reviewed

Electrodiffusion Model Simulation of Ionic Channels: 1D Simulations

Carl Gardner, Wolfgang Nonner and Robert Eisenberg
Journal of computational electronics, Vol.3(1), pp.25-31
2004-01
DOI: https://doi.org/10.1023/B:JCEL.0000029453.09980.fb

Abstract

Appl.Mathematics/Computational Methods of Engineering biological channels diffusion models Electronic and Computer Engineering Engineering ion transport Mathematical and Computational Physics Mechanical Engineering Optical and Electronic Materials
The drift-diffusion (Poisson-Nernst-Planck) model is applied to ionic channels in biological membranes plus surrounding solution baths. Simulations of the K channel in KCl solutions using the TRBDF2 method are presented which show significant boundary layers at the ends of the channel. The computed current-voltage curve for the K channel shows excellent agreement with experimental measurements.

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