Abstract
Purpose of ReviewTo review the safety of performing intravitreal injections in the office compared with the operating room setting.Recent FindingsFew studies directly compare outcomes, including endophthalmitis rate, following intravitreal injections performed in the office versus operating room setting. Instead, the literature on post-injection endophthalmitis consists mostly of retrospective series separately assessing outcomes of injections performed in either the office or in the operating room. These studies consistently show that the rates of endophthalmitis are low in each setting. Of the studies reviewed, 1,220,479 unique intravitreal injections were performed in the office and 285,653 were performed in the operating room. The rate of endophthalmitis was low and similar for each (0.027%).SummaryThe current data suggests that it is safe to perform intravitreal injections in either the office or the operating room.
