Evaluation of a Transgenic Mouse Model of Multiple Sclerosis with Noninvasive Methods

Mabel Enriquez-Algeciras; Di Ding; Tsung-Han Chou; Jianhua Wang; Kyle R Padgett; Vittorio Porciatti; Sanjoy K Bhattacharya

doi:10.1167/iovs.10-6425

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Evaluation of a Transgenic Mouse Model of Multiple Sclerosis with Noninvasive Methods

Journal article

Open access

Peer reviewed

Evaluation of a Transgenic Mouse Model of Multiple Sclerosis with Noninvasive Methods

Mabel Enriquez-Algeciras, Di Ding, Tsung-Han Chou, Jianhua Wang, Kyle R Padgett, Vittorio Porciatti and Sanjoy K Bhattacharya

Investigative ophthalmology & visual science, Vol.52(5), pp.2405-2411

2011-04

DOI: https://doi.org/10.1167/iovs.10-6425

PMCID: PMC3081251

PMID: 21228378

Abstract

A transgenic mice model of multiple sclerosis (ND4 mice) shows progressive visual loss as determined by pattern electroretinogram (PERG). Noninvasive evaluation (PERG, MRI, and OCT) of brain and optic nerve of ND4 mice has been described.

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https://doi.org/10.1167/iovs.10-6425View

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Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.203 Neuromuscular Disorders; 1.203.147 Multiple Sclerosis
Web Of Science research areas: Ophthalmology
ESI research areas: Clinical Medicine

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Details

Title: Evaluation of a Transgenic Mouse Model of Multiple Sclerosis with Noninvasive Methods
Creators: Mabel Enriquez-Algeciras - From the
Di Ding - From the
Tsung-Han Chou - From the
Jianhua Wang - From the
Kyle R Padgett - Radiology, University of Miami, Miami, Florida
Vittorio Porciatti - From the
Sanjoy K Bhattacharya - From the
Publication Details: Investigative ophthalmology & visual science, Vol.52(5), pp.2405-2411
Publisher: Association for Research in Vision and Ophthalmology, Inc
Grant note: EY019077; P30-EY14801 / National Institutes of Health
Academic Unit: Miller School of Medicine; UMMG Department of Ophthalmology; UMMG Dept of Radiation Oncology
Language: English
Resource Type: Journal article
PMID: 21228378
PMCID: PMC3081251
Record Identifier: 991031560277002976