Evidence-based guidelines for the pharmacological treatment of migraine, summary version

Raffaele Ornello; Valeria Caponnetto; Fayyaz Ahmed; Haidar M Al-Khazali; Anna Ambrosini; Sait Ashina; Carlo Baraldi; Alessia Bellotti; Filippo Brighina; Paolo Calabresi; Francesco Casillo; Sabina Cevoli; Shuli Cheng; Chia-Chun Chiang; Alberto Chiarugi; Rune Häckert Christensen; Min Kyung Chu; Gianluca Coppola; Ilenia Corbelli; Santiago Crema; Roberto De Icco; Marina De Tommaso; Cherubino Di Lorenzo; Vincenzo Di Stefano; Hans-Christoph Diener; Esme Ekizoglu; Adriana Fallacara; Valentina Favoni; Kimberly N Garces; Pierangelo Geppetti; Maria Teresa Goicochea; Antonio Granato; Franco Granella; Simona Guerzoni; Woo-Seok Ha; Amr Hassan; Koichi Hirata; Jan Hoffmann; Eva-Maria Hüssler; Mona Hussein; Luigi Francesco Iannone; Bronwyn Jenkins; Alejandro Labastida-Ramirez; Anna Laporta; Morris Levin; Antonino Lupica; Edoardo Mampreso; Daniele Martinelli; Teshamae S Monteith; Ilaria Orologio; Aynur Özge; Li-Ling Hope Pan; Lavindren Luke Panneerchelvam; Mario FP Peres; Marcio Nattan Portes Souza; Patricia Pozo-Rosich; Maria Pia Prudenzano; Silvia Quattrocchi; Innocenzo Rainero; Volodymyr Romanenko; Marina Romozzi; Antonio Russo; Grazia Sances; Paola Sarchielli; Todd J Schwedt; Marcello Silvestro; Diego Belardino Swerts; Cristina Tassorelli; Alessandro Tessitore; Mansoureh Togha; Gloria Vaghi; Shuu-Jiun Wang; Messoud Ashina; Simona Sacco

doi:10.1177/03331024251321500

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Evidence-based guidelines for the pharmacological treatment of migraine, summary version

Journal article

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Evidence-based guidelines for the pharmacological treatment of migraine, summary version

Raffaele Ornello, Valeria Caponnetto, Fayyaz Ahmed, Haidar M Al-Khazali, Anna Ambrosini, Sait Ashina, Carlo Baraldi, Alessia Bellotti, Filippo Brighina, Paolo Calabresi, …

Cephalalgia, Vol.45(4), p.3331024251321500

2025-04

DOI: https://doi.org/10.1177/03331024251321500

PMID: 40277321

Appears in Miller School of Medicine - Latest Publications

Abstract

We here present evidence-based guidelines for the pharmacological treatment of migraine. These guidelines, created by the Italian Society for the Study of Headache and the International Headache Society, aim to offer clear, actionable recommendations to healthcare professionals. They incorporate evidence-based recommendations from randomized controlled trials and expert-based opinions. The guidelines follow the GRADE approach for assessing the quality of evidence. The guideline development involved a systematic review of literature across multiple databases, adherence to Cochrane review methods, and a structured framework for data extraction and interpretation. Although the guidelines provide a robust foundation for migraine treatment, they also highlight gaps in current research, such as the paucity of head-to-head drug comparisons and the need for long-term outcome studies. These guidelines serve as a resource to standardize migraine treatment and promote high-quality care across different healthcare settings.

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Title: Evidence-based guidelines for the pharmacological treatment of migraine, summary version
Creators: Raffaele Ornello - University of L'Aquila
Valeria Caponnetto - University of L'Aquila
Fayyaz Ahmed - University of Hull
Haidar M Al-Khazali - Copenhagen University Hospital
Anna Ambrosini - Istituto Neurologico Mediterraneo
Sait Ashina - Beth Israel Deaconess Medical Center
Carlo Baraldi - University of Modena and Reggio Emilia
Alessia Bellotti - University of Perugia
Filippo Brighina - University of Palermo
Paolo Calabresi - Agostino Gemelli University Polyclinic
Francesco Casillo - Sapienza University of Rome
Sabina Cevoli - Istituto delle Scienze Neurologiche di Bologna
Shuli Cheng - Alfred Health
Chia-Chun Chiang - Mayo Clinic
Alberto Chiarugi - University of Florence
Rune Häckert Christensen - Rigshospitalet
Min Kyung Chu - Yonsei University
Gianluca Coppola - Sapienza University of Rome
Ilenia Corbelli - University of Perugia
Santiago Crema - Neurology Department, Headache Clinic, Fleni, Buenos Aires, Argentina
Roberto De Icco - Fondazione Istituto Neurologico Nazionale Casimiro Mondino
Marina De Tommaso - University of Bari Aldo Moro
Cherubino Di Lorenzo - Sapienza University of Rome
Vincenzo Di Stefano - University of Palermo
Hans-Christoph Diener - University of Duisburg-Essen
Esme Ekizoglu - Istanbul University
Adriana Fallacara - University of Bari Aldo Moro
Valentina Favoni - Istituto delle Scienze Neurologiche di Bologna
Kimberly N Garces - University of Miami
Pierangelo Geppetti - New York University
Maria Teresa Goicochea - Neurology Department, Headache Clinic, Fleni, Buenos Aires, Argentina
Antonio Granato - University of Trieste
Franco Granella - University of Parma
Simona Guerzoni - University of Modena and Reggio Emilia
Woo-Seok Ha - Yonsei University
Amr Hassan - Cairo University
Koichi Hirata - Dokkyo Medical University
Jan Hoffmann - King's College London
Eva-Maria Hüssler - Institut für Medizinische Informatik, Biometrie und Epidemiologie
Mona Hussein - Beni-Suef University
Luigi Francesco Iannone - Mayo Clinic in Arizona
Bronwyn Jenkins - Royal North Shore Hospital
Alejandro Labastida-Ramirez - King's College London
Anna Laporta - University of Bari Aldo Moro
Morris Levin - University of California, San Francisco
Antonino Lupica - University of Palermo
Edoardo Mampreso - Headache Centre, Neurology - Euganea, Health Unit, Padua, Italy
Daniele Martinelli - Fondazione Istituto Neurologico Nazionale Casimiro Mondino
Teshamae S Monteith - University of Miami
Ilaria Orologio - University of Campania "Luigi Vanvitelli"
Aynur Özge - Mersin Üniversitesi
Li-Ling Hope Pan - National Yang Ming Chiao Tung University
Lavindren Luke Panneerchelvam - University of Hull
Mario FP Peres - Universidade de São Paulo
Marcio Nattan Portes Souza - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Patricia Pozo-Rosich - Vall d'Hebron Hospital Universitari
Maria Pia Prudenzano - Polyclinic Medical Center
Silvia Quattrocchi - Istituto delle Scienze Neurologiche di Bologna
Innocenzo Rainero - University of Turin
Volodymyr Romanenko - Ukrainian Military Medical Academy
Marina Romozzi - Università Cattolica del Sacro Cuore
Antonio Russo - University of Campania "Luigi Vanvitelli"
Grazia Sances - Fondazione Istituto Neurologico Nazionale Casimiro Mondino
Paola Sarchielli - University of Perugia
Todd J Schwedt - Mayo Clinic Hospital
Marcello Silvestro - University of Campania "Luigi Vanvitelli"
Diego Belardino Swerts - Universidade de São Paulo
Cristina Tassorelli - Fondazione Istituto Neurologico Nazionale Casimiro Mondino
Alessandro Tessitore - University of Campania "Luigi Vanvitelli"
Mansoureh Togha - Tehran University of Medical Sciences
Gloria Vaghi - Fondazione Istituto Neurologico Nazionale Casimiro Mondino
Shuu-Jiun Wang - National Yang Ming Chiao Tung University
Messoud Ashina - Copenhagen University Hospital
Simona Sacco - University of L'Aquila
Publication Details: Cephalalgia, Vol.45(4), p.3331024251321500
Academic Unit: Miller School of Medicine; UMMG Department of Neurology
Language: English
Resource Type: Journal article
PMID: 40277321
Record Identifier: 991032796083502976