Expression of the Major Histocompatibility Complex Class I Molecule Mamu-A01 Is Associated with Control of Simian Immunodeficiency Virus SIVmac239 Replication

Bianca R Mothé; Jason Weinfurter; Chenxi Wang; William Rehrauer; Nancy Wilson; Todd M Allen; David B Allison; David I Watkins

doi:10.1128/JVI.77.4.2736-2740.2003

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Expression of the Major Histocompatibility Complex Class I Molecule Mamu-A01 Is Associated with Control of Simian Immunodeficiency Virus SIVmac239 Replication

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Expression of the Major Histocompatibility Complex Class I Molecule Mamu-A01 Is Associated with Control of Simian Immunodeficiency Virus SIVmac239 Replication

Bianca R Mothé, Jason Weinfurter, Chenxi Wang, William Rehrauer, Nancy Wilson, Todd M Allen, David B Allison and David I Watkins

Journal of virology, Vol.77(4), pp.2736-2740

2003-02

DOI: https://doi.org/10.1128/JVI.77.4.2736-2740.2003

PMCID: PMC141082

PMID: 12552014

Abstract

Pathogenesis and Immunity

Several HLA alleles are associated with attenuated human immunodeficiency virus disease progression. We explored the relationship between the expression of particular major histocompatibility complex (MHC) class I alleles and viremia in simian immunodeficiency virus SIV mac 239-infected macaques. Of the common MHC class I alleles, animals that expressed Mamu-A*01 exhibited the best control of viral replication.

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Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.66 HIV; 1.66.46 HIV-1
Web Of Science research areas: Virology
ESI research areas: Microbiology

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Details

Title: Expression of the Major Histocompatibility Complex Class I Molecule Mamu-A01 Is Associated with Control of Simian Immunodeficiency Virus SIVmac239 Replication
Creators: Bianca R Mothé - Wisconsin Regional Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715
Jason Weinfurter - Wisconsin Regional Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715
Chenxi Wang - Wisconsin Regional Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715
William Rehrauer - Wisconsin Regional Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715
Nancy Wilson - Wisconsin Regional Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715
Todd M Allen - Wisconsin Regional Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715
David B Allison - Wisconsin Regional Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715
David I Watkins - Wisconsin Regional Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715
Publication Details: Journal of virology, Vol.77(4), pp.2736-2740
Publisher: American Society for Microbiology
Academic Unit: UMMG Department of Pathology
Language: English
Resource Type: Journal article
PMID: 12552014
PMCID: PMC141082
Record Identifier: 991031600745102976