Abstract
AbstractObjective: Patients with cerebellar and non-cerebellar metastases are often included in the same study population, even though posterior fossa lesions typically have different presenting symptoms, clinical outcomes, and complications. This is because the outcomes for patients with cerebellar metastases are unclear.Methods: Adult patients who underwent surgery for an intracranial metastasis (single or multiple) between 2007 and 2011 were retrospectively reviewed. Stepwise multivariate proportional hazards regression analysis was used to identify an association between cerebellar location with survival and recurrence.Results: Of the 708 patients who underwent intracranial metastatic surgery, 140 (19·8%) had surgery for cerebellar metastasis. A cerebellar location was associated with poorer survival [RR (95% CI); 1·231 (1·016–1·523), P = 0·04] and increased spinal recurrence [RR (95% CI); 2·895 (1·491–5·409), P = 0·002], but not local (P = 0·61) or distal recurrence (P = 0·88). The factors in...