Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

Gina M Peloso; Sven J van der Lee; Anita L Destefano; Sudha Seshardi

doi:10.1016/j.dadm.2018.08.008

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Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

Journal article

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Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

Gina M Peloso, Sven J van der Lee, Anita L Destefano and Sudha Seshardi

Alzheimer's & dementia : diagnosis, assessment & disease monitoring, Vol.10(1), pp.595-598

2018

DOI: https://doi.org/10.1016/j.dadm.2018.08.008

PMCID: PMC6215982

PMID: 30422133

Abstract

HDL-C

Genetics

Instrumental variables

Single nucleotide polymorphisms

Blood-Based Biomarkers

Cholesteryl ester transfer protein

• CETP SNPs were not associated with AD in a large sample of AD cases/controls. • Genetically predicted HDL-C through CETP does not associate with AD.

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Title: Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease
Creators: Gina M Peloso - Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
Sven J van der Lee - Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, Netherlands
Anita L Destefano - Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
Sudha Seshardi - NHLBI's Framingham Heart Study, Framingham, MA, USA
Publication Details: Alzheimer's & dementia : diagnosis, assessment & disease monitoring, Vol.10(1), pp.595-598
Publisher: Elsevier
Language: English
Resource Type: Journal article
PMID: 30422133
PMCID: PMC6215982
Record Identifier: 991031576194802976